In 1998 Barker's band, The Aquabats, was opening for blink-182. On this tour blink-182 parted ways with their original drummer, Scott Raynor, and asked Barker to fill the drum stool until the end of the tour. Barker had to learn the entire blink-182 set of 24 songs in just a couple of hours. A few months later, he was asked to join the band full time.
Barker's major musical influences include Latin, jazz, and hip-hop.
In 2003, he appeared on Punk'd, MTV's version of Candid Camera, to take part in a set up bareknuckle boxing match. In 2005, he starred in his own MTV reality show Meet the Barkers, with wife Shanna Moakler, whom he married on October 30, 2004. The couple has one son together, Landon Asher Barker, born October 9, 2003. Travis and Shanna are expecting another child in December 2005.
Recently, he has performed on records by The Black Eyed Peas and Nelly, to name a few.